Prescient Therapeutics Ltd Share Purchase Plan

Prescient Therapeutics (ASX: PTX)

Share Purchase Plan

Share Purchase Plan Details

15 Day VWAP

$0.048*

Offer Price

$0.040

*This offer represents a 16.7% discount to the volume weighted average price (VWAP) over the 15 trading days before the date the SPP was announced. All applications and monies must be received by 5pm (AEST) on 15th July 2025.

“There is a tangible opportunity for us to move into a US$1.8 billion T Cell Lymphoma target market, with several significant near-term milestones. Given Phase 1b results and FDA designations we have received, we are working towards making PTX one of Australia’s biotech success stories and improving the lives of many.”

James Campbell – Non-Executive Chairman

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Overview

Prescient Therapeutics (ASX: PTX) is a late-stage cancer therapeutics business approaching commercialisation for its cancer drug PTX-100 which is currently in Phase 2 trials with the FDA already granting Orphan Drug and Fast Track designations.

Company Highlights 

  • First-in-class technology which could apply to 22% of all cancers.
  • Current focus on Cutaneous T-cell Lymphomas (CTCL), a high-mortality cancer of unmet need.
  • In Phase 2 following strong Phase 1b results including 64% tumor shrinkage or halt and outstanding safety profile.
  • FDA support through Orphan Drug and Fast Track Designation.
  • Potential to turn Phase 2b into a registrational study and, from there, go straight into a US$1.8 billion target market.

Prescient has started dosing patients in their Phase 2a trials and expects several key milestones in the medium term including intermediate data readouts, ongoing FDA feedback and EU Orphan Drug Designation.

While funds raised will go into current CTCL trials for PTX-100, there is also a much wider opportunity, with PTX-100’s first-in-class technology potentially being applicable to 22% of cancer cases.

Offer Details

Prescient Therapeutics (ASX: PTX) has launched a Share Purchase Plan (SPP) at $0.04 per share, representing a discount of 16.7% to PTX’s 15-day VWAP (calculated at market close of 30 June 2025).

Eligible shareholders can apply for a maximum of $30,000 of New Shares.

Use of Funds

The funds raised under the SPP will be used for the following purposes:

  • Funding the continued Phase 2 clinical development of PTX-100 toward potential regulatory approval.
  • Working capital.
  • Cost of the offer.

Should you wish to apply for an amount greater than your allocation, use the same BPAY details to fund the full amount you would like to be allocated.

Refund amounts will be paid either by cheque or by direct credit to the nominated bank account.

Company Presentation

Prescient Therapeutics (ASX: PTX) is a late-stage cancer therapeutics business approaching commercialisation for its first-in-class cancer drug PTX-100 which has already received Orphan Drug and Fast Track designations from the FDA and is currently in Phase 2 trials.

Latest Investor Briefing

41 mins | 29 May, 2025

Presentation Deck

35 pages | May 2025

Q&A with James McDonnell

9 mins | 30 June, 2025

Dr James Campbell

Non-Executive Chairman

Dr James Campbell brings to Prescient a solid track record as a scientist and commercial executive. Dr. Campbell has more than 20 years of international biotechnology research, management and leadership experience and has been involved in the creation and/or transformation of multiple successful Australian and international biotechnology companies.

He is currently CEO of Patrys Limited, a company developing novel antibody therapeutics for oncology.

He was previously the Chief Financial Officer and Chief Operating Officer of Chemgenex, which was acquired by Cephalon for $230 million in 2011. His responsibilities ranged from IP management to licensing and business development and as a member of the executive team, he helped steer and transform the company from a $10 million research based entity to a company with completed clinical trials and regulatory dossiers submitted to the FDA and EMA before its $230 million sale.

Dr Campbell also has experience advising private biotechnology companies in the US and New Zealand with capital raisings and partnering negotiations.

Dr Allen Ebens

Non-Executive Director

Allen Ebens, Ph.D. brings over twenty four years of drug development experience in oncology and hematology, beginning in drug discovery at Exelixis before moving to Genentech where over 11 years he worked from concept to clinic across multiple therapeutic platforms including antibodies, small molecule drugs, antibody-drug conjugates, and T cell recruiting antibodies. Dr. Ebens was recruited from Genentech to establish oncology discovery research at Juno Therapeutics (a CAR-T pioneer), and served as Senior Director, Immune Oncology at NGM Biopharmaceuticals.

He is currently Chief Scientific Officer of Vera Therapeutics. Dr. Ebens’ scientific contributions include numerous peer-reviewed publications of original research, a significant patent portfolio, and the advancement of nine discovery projects from initial concept to clinical development for multiple targets including one marketed therapeutic. He completed his PhD at UCLA and postdoctoral training at UCSF.

Melanie Farris

Non-Executive Director

Ms Farris is an experienced non-executive director, governance, risk and communications professional in the listed, public and not-for-profit sectors, possessing a strong track record in the planning, delivery and oversight of strategic corporate, funding, governance and risk projects across industries including life sciences, investment, agriculture, not-for-profit and music industry marketing.

With extensive senior executive tenure including as chief governance and risk officer, chief financial officer, chief operating officer, group company secretary, senior risk and sustainability advisor, prior roles include with Telix Pharmaceuticals Limited (ASX: TLX), Factor Therapeutics Limited (ASX: FTT), Invion Limited (ASX: IVX), Menzies Research Centre, HRH The Prince of Wales’s Office, Global Asset Management, Imperial Cancer Research Fund, and The Prince’s Foundation.

Melanie holds a Bachelor of Communication (Public Relations), and a Graduate Diploma in Applied Corporate Governance. She is a Fellow of the Governance Institute of Australia, a Fellow of the Chartered Governance Institute (UK) and a Graduate of the Australian Institute of Company Directors.

Dr Ellen Feigal

Non- Executive Director

Dr Feigal is currently a Partner and Head of the Biologics practice at global life sciences advisory firm, NDA Partners LLC, where she leads efforts in designing and executing product development and regulatory strategies in the areas of cell therapies, medical imaging, hematology and oncology. She is also adjunct faculty at the Sandra Day O’Connor College of Law, Arizona State University, where she teaches FDA drug law and medical research ethics and law.

Dr Feigal was formerly Senior Vice President overseeing research and development with the California Institute of Regenerative Medicine, a world-leading research foundation working to accelerate development of new disease modifying treatments and cures for patients with chronic diseases; Executive Medical Director, Global Development at US biotech company Amgen Inc (NASDAQ: AMGN); Vice President of Clinical Sciences at the Translational Genomics Research Institute, and directed the Division of Cancer Treatment and Diagnosis at the National Cancer Institute.

Dr Feigal serves as a Board member for Xencor Inc (NASDAQ: XNCR) a biotechnology company developing engineered antibodies and cytokines for the treatment of cancer and autoimmune diseases. She is also a Director of NextCure (NASDAQ: NXTC) a clinical-stage biotechnology company developing new immunotherapies to treat cancer.

Dr Feigal holds an M.D. from the University of California, Davis School of Medicine. She completed an internal medicine residency at Stanford University and a hematology oncology fellowship at the University of California, San Francisco.

Dr Gavin Shepherd

Non-Executive Director

Dr Shepherd is an accomplished medical professional with 25 years of experience in medicine and a proven track record in driving success in various specialist consulting businesses. After completing his medical qualification at Flinders University, he completed specialist training as a consultant Occupational and Environmental Physician with a fellowship from the Royal Australasian College of Physicians. He graduated dux of his Graduate Diploma in OH+S at Adelaide University and he completed his GAICD qualification in 2011. He is a serial Australian biotech investor and a non-executive director of Lateral Pharma Pty Ltd.

Dr James Campbell

Non-Executive Chairman

Dr James Campbell brings to Prescient a solid track record as a scientist and commercial executive. Dr. Campbell has more than 20 years of international biotechnology research, management and leadership experience and has been involved in the creation and/or transformation of multiple successful Australian and international biotechnology companies.

He is currently CEO of Patrys Limited, a company developing novel antibody therapeutics for oncology.

He was previously the Chief Financial Officer and Chief Operating Officer of Chemgenex, which was acquired by Cephalon for $230 million in 2011. His responsibilities ranged from IP management to licensing and business development and as a member of the executive team, he helped steer and transform the company from a $10 million research based entity to a company with completed clinical trials and regulatory dossiers submitted to the FDA and EMA before its $230 million sale.

Dr Campbell also has experience advising private biotechnology companies in the US and New Zealand with capital raisings and partnering negotiations.

Dr Allen Ebens

Non-Executive Director

Allen Ebens, Ph.D. brings over twenty four years of drug development experience in oncology and hematology, beginning in drug discovery at Exelixis before moving to Genentech where over 11 years he worked from concept to clinic across multiple therapeutic platforms including antibodies, small molecule drugs, antibody-drug conjugates, and T cell recruiting antibodies. Dr. Ebens was recruited from Genentech to establish oncology discovery research at Juno Therapeutics (a CAR-T pioneer), and served as Senior Director, Immune Oncology at NGM Biopharmaceuticals.

He is currently Chief Scientific Officer of Vera Therapeutics. Dr. Ebens’ scientific contributions include numerous peer-reviewed publications of original research, a significant patent portfolio, and the advancement of nine discovery projects from initial concept to clinical development for multiple targets including one marketed therapeutic. He completed his PhD at UCLA and postdoctoral training at UCSF.

Melanie Farris

Non-Executive Director

Ms Farris is an experienced non-executive director, governance, risk and communications professional in the listed, public and not-for-profit sectors, possessing a strong track record in the planning, delivery and oversight of strategic corporate, funding, governance and risk projects across industries including life sciences, investment, agriculture, not-for-profit and music industry marketing.

With extensive senior executive tenure including as chief governance and risk officer, chief financial officer, chief operating officer, group company secretary, senior risk and sustainability advisor, prior roles include with Telix Pharmaceuticals Limited (ASX: TLX), Factor Therapeutics Limited (ASX: FTT), Invion Limited (ASX: IVX), Menzies Research Centre, HRH The Prince of Wales’s Office, Global Asset Management, Imperial Cancer Research Fund, and The Prince’s Foundation.

Melanie holds a Bachelor of Communication (Public Relations), and a Graduate Diploma in Applied Corporate Governance. She is a Fellow of the Governance Institute of Australia, a Fellow of the Chartered Governance Institute (UK) and a Graduate of the Australian Institute of Company Directors.

Dr Ellen Feigal

Non- Executive Director

Dr Feigal is currently a Partner and Head of the Biologics practice at global life sciences advisory firm, NDA Partners LLC, where she leads efforts in designing and executing product development and regulatory strategies in the areas of cell therapies, medical imaging, hematology and oncology. She is also adjunct faculty at the Sandra Day O’Connor College of Law, Arizona State University, where she teaches FDA drug law and medical research ethics and law.

Dr Feigal was formerly Senior Vice President overseeing research and development with the California Institute of Regenerative Medicine, a world-leading research foundation working to accelerate development of new disease modifying treatments and cures for patients with chronic diseases; Executive Medical Director, Global Development at US biotech company Amgen Inc (NASDAQ: AMGN); Vice President of Clinical Sciences at the Translational Genomics Research Institute, and directed the Division of Cancer Treatment and Diagnosis at the National Cancer Institute.

Dr Feigal serves as a Board member for Xencor Inc (NASDAQ: XNCR) a biotechnology company developing engineered antibodies and cytokines for the treatment of cancer and autoimmune diseases. She is also a Director of NextCure (NASDAQ: NXTC) a clinical-stage biotechnology company developing new immunotherapies to treat cancer.

Dr Feigal holds an M.D. from the University of California, Davis School of Medicine. She completed an internal medicine residency at Stanford University and a hematology oncology fellowship at the University of California, San Francisco.

Dr Gavin Shepherd

Non-Executive Director

Dr Shepherd is an accomplished medical professional with 25 years of experience in medicine and a proven track record in driving success in various specialist consulting businesses. After completing his medical qualification at Flinders University, he completed specialist training as a consultant Occupational and Environmental Physician with a fellowship from the Royal Australasian College of Physicians. He graduated dux of his Graduate Diploma in OH+S at Adelaide University and he completed his GAICD qualification in 2011. He is a serial Australian biotech investor and a non-executive director of Lateral Pharma Pty Ltd.

James McDonnell

CEO

James McDonnell is a seasoned leader in the biopharmaceutical industry, bringing over 25 years of global experience in pharmaceuticals, with a particular focus on blood disorders and hematological malignancies such as Myeloma, Myelodysplasia, and CML.

Throughout his career, James has held senior leadership roles at renowned pharmaceutical companies, including Pharmion and CSL Vifor. At Pharmion, he spearheaded the growth of its oncology and hematology portfolio as Head of Global Marketing, contributing significantly to the company’s acquisition by Celgene Corporation for US$2.9 billion. Most recently, James served as Global Commercial Lead for Patient Blood Management at CSL Vifor, where he drove key enterprise-wide strategic initiatives.

James is a registered pharmacist and a member of the Royal Pharmaceutical Society. He holds a Graduate Diploma in Marketing from Monash University and is a graduate of the Australian Institute of Company Directors.

Dr Rebecca Tunstall

Chief Operating Officer

Dr Rebecca Tunstall is a highly accomplished executive in the Australian biotechnology and pharmaceutical sectors, with nearly 20 years of experience in strategy, oncology product development, and operational excellence.

Across her career, Rebecca has held pivotal leadership positions at prominent organisations including GSK, MTPConnect, and Patrys Ltd. At GSK, she built significant value over 13 years in senior oncology roles, developing deep expertise in therapeutic developmentt and commercialisation. As Senior Director of Stakeholder Engagement at MTPConnect, she orchestrated collaborative initiatives connecting Australia’s medtech and biotech ecosystem with industry and government partners. Most recently, Rebecca served as Vice President of Corporate Development at Patrys Ltd (ASX:PAB), where she executed critical business development and cross-functional initiatives.

Rebecca holds a PhD and Bachelor of Applied Science with Honours, and is a graduate of the Australian Institute of Company Directors.

Dr. Marissa Lim

Chief Medical Officer
  • 20 years of experience in the pharmaceutical and biotechnology industries.
  • Served as Clinical and Medical Advisor, as well as the CMO to several biotechnology companies.
  • Previously held senior positions at Vifor Pharma, Ipsen and Telix.
  • Strong background in clinical development and regulatory affairs.
  • Successful launches of haematology and oncology therapies.

James McDonnell

CEO

James McDonnell is a seasoned leader in the biopharmaceutical industry, bringing over 25 years of global experience in pharmaceuticals, with a particular focus on blood disorders and hematological malignancies such as Myeloma, Myelodysplasia, and CML.

Throughout his career, James has held senior leadership roles at renowned pharmaceutical companies, including Pharmion and CSL Vifor. At Pharmion, he spearheaded the growth of its oncology and hematology portfolio as Head of Global Marketing, contributing significantly to the company’s acquisition by Celgene Corporation for US$2.9 billion. Most recently, James served as Global Commercial Lead for Patient Blood Management at CSL Vifor, where he drove key enterprise-wide strategic initiatives.

James is a registered pharmacist and a member of the Royal Pharmaceutical Society. He holds a Graduate Diploma in Marketing from Monash University and is a graduate of the Australian Institute of Company Directors.

Dr Rebecca Tunstall

Chief Operating Officer

Dr Rebecca Tunstall is a highly accomplished executive in the Australian biotechnology and pharmaceutical sectors, with nearly 20 years of experience in strategy, oncology product development, and operational excellence.

Across her career, Rebecca has held pivotal leadership positions at prominent organisations including GSK, MTPConnect, and Patrys Ltd. At GSK, she built significant value over 13 years in senior oncology roles, developing deep expertise in therapeutic developmentt and commercialisation. As Senior Director of Stakeholder Engagement at MTPConnect, she orchestrated collaborative initiatives connecting Australia’s medtech and biotech ecosystem with industry and government partners. Most recently, Rebecca served as Vice President of Corporate Development at Patrys Ltd (ASX:PAB), where she executed critical business development and cross-functional initiatives.

Rebecca holds a PhD and Bachelor of Applied Science with Honours, and is a graduate of the Australian Institute of Company Directors.

Dr. Marissa Lim

Chief Medical Officer
  • 20 years of experience in the pharmaceutical and biotechnology industries.
  • Served as Clinical and Medical Advisor, as well as the CMO to several biotechnology companies.
  • Previously held senior positions at Vifor Pharma, Ipsen and Telix.
  • Strong background in clinical development and regulatory affairs.
  • Successful launches of haematology and oncology therapies.

Latest News

Request Share Purchase Plan

What is a 708 investor?

By clicking submit, I agree to the terms of the Reach Markets Financial Services Guide that includes the Privacy Statement. Reach Markets provide Corporate Advisory Services to Prescient Therapeutics Limited, and will receive fees for its role in managing this offer based on the uptake by investors.

The Share Purchase Plan (SPP) is not an offer of securities in any place outside Australia or New Zealand and does not take into account your individual investment objectives, financial situation or particular needs. An investment in the Company is speculative. The information in the SPP Booklet is not investment advice or a recommendation to acquire SPP Shares. Therefore, you should obtain independent financial and taxation advice before making an investment decision. Before making an investment decision, you should read the SPP terms in the Offer Booklet.

 

*Wholesale 708 Sophisticated Investors are individuals or entities who generally qualify under Sections 708(8) and s761G(7) of the Corporations Act based on the gross income and/or net assets test verified by a qualified accountant.

  • A gross income of $250,000 or more per annum in each of the previous two financial years; or
  • Net assets of at least $2.5 million; and
  • A verified Qualified Accountant’s certificate given no more than two (2) years ago confirming the Sophisticated Investor status.  Please refer to the Corporations Act:  Specifically Section 708(08) and Section s761G(7)

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